A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is what role(s) this feedback plays in our ability to he...

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Main Authors: Taranda, Julian, Maison, Stéphane F, Ballestero, Jimena A, Katz, Eleonora, Savino, Jessica, Vetter, Douglas E, Boulter, Jim, Liberman, M. Charles, Fuchs, Paul A, Elgoyhen, A. Belén
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628405/
https://ncbi.nlm.nih.gov/pubmed/19166271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000018
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