A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is what role(s) this feedback plays in our ability to he...

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Détails bibliographiques
Auteurs principaux: Taranda, Julian, Maison, Stéphane F, Ballestero, Jimena A, Katz, Eleonora, Savino, Jessica, Vetter, Douglas E, Boulter, Jim, Liberman, M. Charles, Fuchs, Paul A, Elgoyhen, A. Belén
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628405/
https://ncbi.nlm.nih.gov/pubmed/19166271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000018
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