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CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression
Reactive species derived from cell oxygenation processes play an important role in vascular homeostasis and the pathogenesis of many diseases including retinopathy of prematurity. We show that CYP1B1-deficient (CYP1B1(−/−)) mice fail to elicit a neovascular response during oxygen-induced ischemic re...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628380/ https://ncbi.nlm.nih.gov/pubmed/19005183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-145219 |
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