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CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress

We have recently shown that deletion of constitutively expressed CYP1B1 is associated with attenuation of retinal endothelial cell (EC) capillary morphogenesis (CM) in vitro and angiogenesis in vivo. This was largely caused by increased intracellular oxidative stress and increased production of thro...

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Detalhes bibliográficos
Main Authors: Tang, Yixin, Scheef, Elizabeth A., Gurel, Zafer, Sorenson, Christine M., Jefcoate, Colin R., Sheibani, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838582/
https://ncbi.nlm.nih.gov/pubmed/20032512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00153.2009
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