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Lack of Thrombospondin-1 and Exacerbation of Choroidal Neovascularization

PURPOSE: To assess the impact of thrombospondin-1 (TSP1) deficiency on choroidal neovascularization (CNV) and determine whether administration of a TSP1 antiangiogenic mimetic peptide attenuates CNV. METHODS: The impact of TSP1-deficiency on laser induced CNV was assessed using wild type (TSP1+/+) a...

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Bibliographic Details
Main Authors: Wang, Shoujian, Sorenson, Christine M., Sheibani, Nader
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404202/
https://ncbi.nlm.nih.gov/pubmed/22232368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archopthalmol.2011.1892
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