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Suppression of Thrombospondin-1 Expression during Uveal Melanoma Progression and its Utilization as Potential Therapeutic
OBJECTIVE: To determine whether expression of thrombospondin-1 (TSP1), an endogenous inhibitor of angiogenesis, is down-regulated during progression of uveal melanoma and if administration of TSP1 and/or its antiangiogenic peptides attenuate tumor growth. METHODS: Tyr-tag transgenic mice were used f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381901/ https://ncbi.nlm.nih.gov/pubmed/22411663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archopthalmol.2011.1503 |
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