Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization

Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss. Thrombospondin-1 (TSP1) is a matricellular protein that negatively regulates angiogenesis and inflammation in the eye. It aids ocular vascular...

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Udgivet i:Front Cell Dev Biol
Main Authors: Sorenson, Christine M., Wang, Shoujian, Darjatmoko, Soesiawati R., Gurel, Zafer, Liu, Bo, Sheibani, Nader
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097095/
https://ncbi.nlm.nih.gov/pubmed/33968943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.671989
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