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Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization

Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss. Thrombospondin-1 (TSP1) is a matricellular protein that negatively regulates angiogenesis and inflammation in the eye. It aids ocular vascular...

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Библиографические подробности
Опубликовано в: :Front Cell Dev Biol
Главные авторы: Sorenson, Christine M., Wang, Shoujian, Darjatmoko, Soesiawati R., Gurel, Zafer, Liu, Bo, Sheibani, Nader
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097095/
https://ncbi.nlm.nih.gov/pubmed/33968943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.671989
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