Subtractive Hybridization Reveals a Type I Polyketide Synthase Locus Specific to Mycobacterium ulcerans

Mycobacterium ulcerans causes Buruli ulcer, the third most prevalent mycobacterial infection of immunocompetent humans after tuberculosis and leprosy. Recent work has shown that the production by M. ulcerans of mycolactone, a novel polyketide, may partly explain the pathogenesis of Buruli ulcer. To...

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Bibliographic Details
Main Authors: Jenkin, Grant A., Stinear, Timothy P., Johnson, Paul D. R., Davies, John K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC262701/
https://ncbi.nlm.nih.gov/pubmed/14617651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.23.6870-6882.2003
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