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Subtractive Hybridization Reveals a Type I Polyketide Synthase Locus Specific to Mycobacterium ulcerans

Mycobacterium ulcerans causes Buruli ulcer, the third most prevalent mycobacterial infection of immunocompetent humans after tuberculosis and leprosy. Recent work has shown that the production by M. ulcerans of mycolactone, a novel polyketide, may partly explain the pathogenesis of Buruli ulcer. To...

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Detalhes bibliográficos
Main Authors: Jenkin, Grant A., Stinear, Timothy P., Johnson, Paul D. R., Davies, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262701/
https://ncbi.nlm.nih.gov/pubmed/14617651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.23.6870-6882.2003
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