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Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses

The cooperative activity of protein tyrosine kinases and phosphatases plays a central role in regulation of T cell receptor (TCR) signal strength. Perturbing this balance, and thus the threshold for TCR signals, has profound impacts on T cell development and function. We previously generated mice co...

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Bibliografski detalji
Glavni autori: Hermiston, Michelle L., Zikherman, Julie, Tan, Allison L., Lam, Viola C., Cresalia, Nicole M., Oksenberg, Nir, Goren, Nira, Brassat, David, Oksenberg, Jorge R., Weiss, Arthur
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626740/
https://ncbi.nlm.nih.gov/pubmed/19129486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811647106
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