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The yeast Sup35NM domain propagates as a prion in mammalian cells
Prions are infectious, self-propagating amyloid-like protein aggregates of mammals and fungi. We have studied aggregation propensities of a yeast prion domain in cell culture to gain insights into general mechanisms of prion replication in mammalian cells. Here, we report the artificial transmission...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626725/ https://ncbi.nlm.nih.gov/pubmed/19114662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811571106 |
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