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Two prion variants of Sup35p have in-register parallel β-sheet structures, independent of hydration

The [PSI(+)] prion is a self-propagating amyloid of the Sup35 protein, normally a subunit of the translation termination factor, but impaired in this vital function when in the amyloid form. The Sup35 N, M and C domains are the amino-terminal prion domain, a connecting polar domain and the essential...

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Bibliographic Details
Main Authors: Shewmaker, Frank, Kryndushkin, Dmitry, Chen, Bo, Tycko, Robert, Wickner, Reed B.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744896/
https://ncbi.nlm.nih.gov/pubmed/19408895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900345q
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