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Amyloid of Rnq1p, the basis of the [PIN(+)] prion, has a parallel in-register β-sheet structure
The [PIN(+)] prion, a self-propagating amyloid form of Rnq1p, increases the frequency with which the [PSI(+)] or [URE3] prions arise de novo. Like the prion domains of Sup35p and Ure2p, Rnq1p is rich in N and Q residues, but rnq1Δ strains have no known phenotype except for inability to propagate the...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268149/ https://ncbi.nlm.nih.gov/pubmed/18268327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712032105 |
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