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Amyloid of Rnq1p, the basis of the [PIN(+)] prion, has a parallel in-register β-sheet structure

The [PIN(+)] prion, a self-propagating amyloid form of Rnq1p, increases the frequency with which the [PSI(+)] or [URE3] prions arise de novo. Like the prion domains of Sup35p and Ure2p, Rnq1p is rich in N and Q residues, but rnq1Δ strains have no known phenotype except for inability to propagate the...

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Bibliografische gegevens
Hoofdauteurs: Wickner, Reed B., Dyda, Fred, Tycko, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268149/
https://ncbi.nlm.nih.gov/pubmed/18268327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712032105
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