Simian-Human Immunodeficiency Virus Escape from Cytotoxic T-Lymphocyte Recognition at a Structurally Constrained Epitope

Virus-specific cytotoxic T lymphocytes (CTL) exert intense selection pressure on replicating simian immunodeficiency virus (SIV) and human immunodeficiency virus type 1 (HIV-1) in infected individuals. The immunodominant Mamu-A(*)01-restricted Gag p11C, C-M epitope is highly conserved among all sequ...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Peyerl, Fred W., Barouch, Dan H., Yeh, Wendy W., Bazick, Heidi S., Kunstman, Jennifer, Kunstman, Kevin J., Wolinsky, Steven M., Letvin, Norman L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14610180/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.23.12572-12578.2003
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