Elicitation of High-Frequency Cytotoxic T-Lymphocyte Responses against both Dominant and Subdominant Simian-Human Immunodeficiency Virus Epitopes by DNA Vaccination of Rhesus Monkeys

Increasing evidence suggests that the generation of cytotoxic T-lymphocyte (CTL) responses specific for a diversity of viral epitopes will be needed for an effective human immunodeficiency virus type 1 (HIV-1) vaccine. Here, we determine the frequencies of CTL responses specific for the simian immun...

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Bibliographic Details
Main Authors: Barouch, Dan H., Craiu, Abie, Santra, Sampa, Egan, Michael A., Schmitz, Jörn E., Kuroda, Marcelo J., Fu, Tong-Ming, Nam, Jae-Hwan, Wyatt, Linda S., Lifton, Michelle A., Krivulka, Georgia R., Nickerson, Christine E., Lord, Carol I., Moss, Bernard, Lewis, Mark G., Hirsch, Vanessa M., Shiver, John W., Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114830/
https://ncbi.nlm.nih.gov/pubmed/11160750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2462-2467.2001
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