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The Death Domain Kinase RIP1 Is Essential for Tumor Necrosis Factor Alpha Signaling to p38 Mitogen-Activated Protein Kinase
The cytokine tumor necrosis factor alpha (TNF-α) stimulates the NF-κB, SAPK/JNK, and p38 mitogen-activated protein (MAP) kinase pathways by recruiting RIP1 and TRAF2 proteins to the tumor necrosis factor receptor 1 (TNFR1). Genetic studies have revealed that RIP1 links the TNFR1 to the IκB kinase (I...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262426/ https://ncbi.nlm.nih.gov/pubmed/14585994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8377-8385.2003 |
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