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Activation of p38 Mitogen-Activated Protein Kinase In Vivo Selectively Induces Apoptosis of CD8(+) but Not CD4(+) T Cells

CD4(+) and CD8(+) T cells play specific roles during an immune response. Different molecular mechanisms could regulate the proliferation, death, and effector functions of these two subsets of T cells. The p38 mitogen-activated protein (MAP) kinase pathway is induced by cytokines and environmental st...

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Main Authors: Merritt, Chris, Enslen, Hervé, Diehl, Nicole, Conze, Dietrich, Davis, Roger J., Rincón, Mercedes
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC85211/
https://ncbi.nlm.nih.gov/pubmed/10629051
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