The Death Domain Kinase RIP1 Is Essential for Tumor Necrosis Factor Alpha Signaling to p38 Mitogen-Activated Protein Kinase

The cytokine tumor necrosis factor alpha (TNF-α) stimulates the NF-κB, SAPK/JNK, and p38 mitogen-activated protein (MAP) kinase pathways by recruiting RIP1 and TRAF2 proteins to the tumor necrosis factor receptor 1 (TNFR1). Genetic studies have revealed that RIP1 links the TNFR1 to the IκB kinase (I...

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Detalhes bibliográficos
Principais autores: Lee, Thomas H., Huang, Qiaojia, Oikemus, Sarah, Shank, Jennifer, Ventura, Juan-Jose, Cusson, Nicole, Vaillancourt, Richard R., Su, Bing, Davis, Roger J., Kelliher, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262426/
https://ncbi.nlm.nih.gov/pubmed/14585994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8377-8385.2003
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