The Mechanism of Nucleotide Incorporation by Human DNA Polymerase η Differs from That of the Yeast Enzyme

DNA polymerase η (Polη) catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers, and inactivation of Polη in humans causes the cancer-prone syndrome, the variant form of xeroderma pigmentosum. Pre-steady-state kinetic studies of yeast Polη have indicated that the...

Descripción completa

Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Washington, M. Todd, Johnson, Robert E., Prakash, Louise, Prakash, Satya
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2003
Materias:	DNA Dynamics and Chromosome Structure
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8316-8322.2003
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!