The Mechanism of Nucleotide Incorporation by Human DNA Polymerase η Differs from That of the Yeast Enzyme
DNA polymerase η (Polη) catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers, and inactivation of Polη in humans causes the cancer-prone syndrome, the variant form of xeroderma pigmentosum. Pre-steady-state kinetic studies of yeast Polη have indicated that the...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
|---|---|
| Principais autores: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2003
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8316-8322.2003 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|