Human Heterochromatin Protein 1 Isoforms HP1(Hsα) and HP1(Hsβ) Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation

Telomeres are associated with the nuclear matrix and are thought to be heterochromatic. We show here that in human cells the overexpression of green fluorescent protein-tagged heterochromatin protein 1 (GFP-HP1) or nontagged HP1 isoforms HP1(Hsα) or HP1(Hsβ), but not HP1(Hsγ), results in decreased a...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Sharma, Girdhar G., Hwang, Kyu-kye, Pandita, Raj K., Gupta, Arun, Dhar, Sonu, Parenteau, Julie, Agarwal, Manjula, Worman, Howard J., Wellinger, Raymund J., Pandita, Tej K.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2003
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8363-8376.2003
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!