Human Heterochromatin Protein 1 Isoforms HP1(Hsα) and HP1(Hsβ) Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation

Telomeres are associated with the nuclear matrix and are thought to be heterochromatic. We show here that in human cells the overexpression of green fluorescent protein-tagged heterochromatin protein 1 (GFP-HP1) or nontagged HP1 isoforms HP1(Hsα) or HP1(Hsβ), but not HP1(Hsγ), results in decreased a...

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書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Sharma, Girdhar G., Hwang, Kyu-kye, Pandita, Raj K., Gupta, Arun, Dhar, Sonu, Parenteau, Julie, Agarwal, Manjula, Worman, Howard J., Wellinger, Raymund J., Pandita, Tej K.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2003
主題:	Cell Growth and Development
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8363-8376.2003
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