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Sox3 Is Required for Gonadal Function, but Not Sex Determination, in Males and Females
Sox3 is expressed in developing gonads and in the brain. Evolutionary evidence suggests that the X-chromosomal Sox3 gene may be the ancestral precursor of Sry, a sex-determining gene, and Sox3 has been proposed to play a role in sex determination. However, patients with mutations in SOX3 exhibit nor...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262333/ https://ncbi.nlm.nih.gov/pubmed/14585968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8084-8091.2003 |
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