Phenotype of arylsulfatase A-deficient mice: Relationship to human metachromatic leukodystrophy

Metachromatic leukodystrophy is a lysosomal sphingolipid storage disorder caused by the deficiency of arylsulfatase A. The disease is characterized by progressive demyelination, causing various neurologic symptoms. Since no naturally occurring animal model of the disease is available, we have genera...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hess, Barbara, Saftig, Paul, Hartmann, Dieter, Coenen, Ruth, Lüllmann-Rauch, Renate, Goebel, Hans H., Evers, Meike, von Figura, Kurt, D’Hooge, Rudi, Nagels, Guy, De Deyn, Peter, Peters, Christoph, Gieselmann, Volkmar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14821
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