Phenotype of arylsulfatase A-deficient mice: Relationship to human metachromatic leukodystrophy

Metachromatic leukodystrophy is a lysosomal sphingolipid storage disorder caused by the deficiency of arylsulfatase A. The disease is characterized by progressive demyelination, causing various neurologic symptoms. Since no naturally occurring animal model of the disease is available, we have genera...

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Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hess, Barbara, Saftig, Paul, Hartmann, Dieter, Coenen, Ruth, Lüllmann-Rauch, Renate, Goebel, Hans H., Evers, Meike, von Figura, Kurt, D’Hooge, Rudi, Nagels, Guy, De Deyn, Peter, Peters, Christoph, Gieselmann, Volkmar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14821
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