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COX-2 expression and function in the hyperalgesic response to paw inflammation in mice

Peripheral inflammation and edema are often accompanied by primary and secondary hyperalgesia which are mediated by both peripheral and central mechanisms. The role of cyclooxygenase-2 (COX-2)-mediated prostanoid production in hyperalgesia is a topic of substantial current interest. We have establis...

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Autors principals: Jain, Naveen K., Ishikawa, Tomo-o, Spigelman, Igor, Herschman, Harvey R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615797/
https://ncbi.nlm.nih.gov/pubmed/18829279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2008.08.001
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