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Feedback regulation of Cyclooxygenase-2 transcription ex vivo and in vivo
Cyclooxygenase-2 (COX-2) is a rate-limiting enzyme for prostaglandin biosynthesis. Its inducible expression is regulated by complex pathways. To monitor Cox-2 transcriptional activity in vivo, we generated a knock-in mouse expressing a firefly luciferase reporter. In this study we examined, by compa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637547/ https://ncbi.nlm.nih.gov/pubmed/19061862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.11.099 |
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