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PARP-1 Inhibits Glycolysis in Ischemic Kidneys

After ischemic renal injury (IRI), selective damage occurs in the S(3) segments of the proximal tubules as a result of inhibition of glycolysis, but the mechanism of this inhibition is unknown. We previously reported that inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) activity protects against...

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Hlavní autoři: Devalaraja-Narashimha, Kishor, Padanilam, Babu J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615730/
https://ncbi.nlm.nih.gov/pubmed/19056868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030325
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