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TIGAR regulates glycolysis in ischemic kidney proximal tubules

Tp53-induced glycolysis and apoptosis regulator (TIGAR) activation blocks glycolytic ATP synthesis by inhibiting phosphofructokinase-1 activity. Our data indicate that TIGAR is selectively induced and activated in renal outermedullary proximal straight tubules (PSTs) after ischemia-reperfusion injur...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Kim, Jinu, Devalaraja-Narashimha, Kishor, Padanilam, Babu J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329488/
https://ncbi.nlm.nih.gov/pubmed/25503731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00459.2014
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