Cortical Neurons Transgenic for Human Aβ40 or Aβ42 Have Similar Vulnerability to Apoptosis despite Their Different Amyloidogenic Properties

Alzheimer's disease (AD) is a leading cause of chronic dementia in the United States. Its incidence is increasing with an attendant increase in associated health care costs. Amyloid β peptide (Aβ; a 39-42 amino acid molecule) is the major component of senile plaques, the hallmark lesion of AD....

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Bibliografske podrobnosti
Main Authors: Shiwany, Najeeb A., Xie, Jun, Guo, Qing
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2008
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615591/
https://ncbi.nlm.nih.gov/pubmed/19158991
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