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Cortical Neurons Transgenic for Human Aβ40 or Aβ42 Have Similar Vulnerability to Apoptosis despite Their Different Amyloidogenic Properties
Alzheimer's disease (AD) is a leading cause of chronic dementia in the United States. Its incidence is increasing with an attendant increase in associated health care costs. Amyloid β peptide (Aβ; a 39-42 amino acid molecule) is the major component of senile plaques, the hallmark lesion of AD....
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
e-Century Publishing Corporation
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615591/ https://ncbi.nlm.nih.gov/pubmed/19158991 |
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