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Multiple Anaphase-promoting Complex/Cyclosome Degrons Mediate the Degradation of Human Sgo1
Shugoshin 1 (Sgo1) protects centromeric sister-chromatid cohesion in early mitosis and, thus, prevents premature sister-chromatid separation. The protein level of Sgo1 is regulated during the cell cycle; it peaks in mitosis and is down-regulated in G(1)/S. Here we show that Sgo1 is degraded during t...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615523/ https://ncbi.nlm.nih.gov/pubmed/19015261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807083200 |
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