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Constitutive Endocytosis of the Chemokine CX(3)CL1 Prevents Its Degradation by Cell Surface Metalloproteases

CX(3)CL1, a chemokine with transmembrane and soluble species, plays a key role in inflammation by acting as both chemoattractant and adhesion molecule. CX(3)CL1 is the only chemokine known to undergo constitutive internalization, raising the possibility that dynamic equilibrium between the endocytic...

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Detalhes bibliográficos
Main Authors: Huang, Yi-Wei, Su, Paul, Liu, Guang Ying, Crow, Min Rui, Chaukos, Deanna, Yan, Harry, Robinson, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785596/
https://ncbi.nlm.nih.gov/pubmed/19723636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045682
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