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Constitutive Endocytosis and Degradation of the Pre-T Cell Receptor

The pre-T cell receptor (TCR) signals constitutively in the absence of putative ligands on thymic stroma and signal transduction correlates with translocation of the pre-TCR into glycolipid-enriched microdomains (rafts) in the plasma membrane. Here, we show that the pre-TCR is constitutively routed...

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Bibliografiske detaljer
Main Authors: Panigada, Maddalena, Porcellini, Simona, Barbier, Eliane, Hoeflinger, Sonja, Cazenave, Pierre-André, Gu, Hua, Band, Hamid, von Boehmer, Harald, Grassi, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193560/
https://ncbi.nlm.nih.gov/pubmed/12070286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020047
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