S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1

Proteolytic processing of amyloid precursor protein (APP) by β- and γ-secretases generates β-amyloid (Aβ) peptides, which accumulate in the brains of individuals affected by Alzheimer disease. Detergent-resistant membrane microdomains (DRM) rich in cholesterol and sphingolipid, termed lipid rafts, h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cheng, Haipeng, Vetrivel, Kulandaivelu S., Drisdel, Renaldo C., Meckler, Xavier, Gong, Ping, Leem, Jae Yoon, Li, Tong, Carter, Meghan, Chen, Ying, Nguyen, Phuong, Iwatsubo, Takeshi, Tomita, Taisuke, Wong, Philip C., Green, William N., Kounnas, Maria Z., Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615504/
https://ncbi.nlm.nih.gov/pubmed/19028695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806380200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados