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Development of molecular probes for second site screening and design of protein tyrosine phosphatase inhibitors
We report on the design, synthesis and evaluation of series of furanyl-salicyl-nitroxide derivatives, as effective chemical probes for second site screening against phosphotyrosine phosphatases (PTPs) using NMR-based techniques. The compounds have been tested against a panel of PTPs to asses their a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615387/ https://ncbi.nlm.nih.gov/pubmed/17394300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061481l |
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