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Dominant negative inhibition by fragments of a monomeric enzyme

Dominant negative inhibition is most commonly seen when a mutant subunit of a multisubunit protein is coexpressed with the wild-type protein so that assembly of a functional oligomer is impaired. By analogy, it should be possible to interfere with the functional assembly of a monomeric enzyme by int...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Michaels, John-Edward A., Schimmel, Paul, Shiba, Kiyotaka, Miller, W. Todd
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences of the USA 1996
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC26153/
https://ncbi.nlm.nih.gov/pubmed/8962072
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