Dominant negative inhibition by fragments of a monomeric enzyme
Dominant negative inhibition is most commonly seen when a mutant subunit of a multisubunit protein is coexpressed with the wild-type protein so that assembly of a functional oligomer is impaired. By analogy, it should be possible to interfere with the functional assembly of a monomeric enzyme by int...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26153/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14452 |
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