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Voltage-dependent K(+) channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

Voltage-dependent K(+) (Kv) channels underlie action potentials through gating conformational changes that are driven by membrane voltage. In this study of the paddle chimera Kv channel, we demonstrate that the rate of channel opening, the voltage dependence of the open probability, and the maximum...

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Bibliografski detalji
Glavni autori: Schmidt, Daniel, MacKinnon, Roderick
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614752/
https://ncbi.nlm.nih.gov/pubmed/19050073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810187105
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