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A genetically encoded fluorescent sensor of ERK activity

The activity of the ERK has complex spatial and temporal dynamics that are important for the specificity of downstream effects. However, current biochemical techniques do not allow for the measurement of ERK signaling with fine spatiotemporal resolution. We developed a genetically encoded, FRET-base...

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Bibliografiske detaljer
Main Authors: Harvey, Christopher D., Ehrhardt, Anka G., Cellurale, Cristina, Zhong, Haining, Yasuda, Ryohei, Davis, Roger J., Svoboda, Karel
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614750/
https://ncbi.nlm.nih.gov/pubmed/19033456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804598105
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