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Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection

We have developed genetically encoded fluorescent sensors for reduced nicotinamide adenine dinucleotide (NADH), which manifest a large change in fluorescence upon NADH binding. We demonstrate the utility of these sensors in mammalian cells by monitoring the dynamic changes in NADH levels in subcellu...

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Detalhes bibliográficos
Main Authors: Zhao, Yuzheng, Jin, Jing, Hu, Qingxun, Zhou, Hai-Meng, Yi, Jing, Yu, Zhenhang, Xu, Lei, Wang, Xue, Yang, Yi, Loscalzo, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253140/
https://ncbi.nlm.nih.gov/pubmed/21982715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.09.004
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