Illuminating NAD(+) Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor

Understanding of NAD(+) metabolism provides many critical insights into health and diseases; yet highly sensitive and specific detection of NAD(+) metabolism in live cells and in vivo remains difficult. Here we present ratiometric, highly responsive genetically encoded fluorescent indicators, FiNad,...

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Veröffentlicht in:Dev Cell
Hauptverfasser: Zou, Yejun, Wang, Aoxue, Huang, Li, Zhu, Xudong, Hu, Qingxun, Zhang, Yinan, Chen, Xianjun, Li, Fengwen, Wang, Qiaohui, Wang, Hu, Liu, Renmei, Zuo, Fangting, Li, Ting, Yao, Jing, Qian, Yajie, Shi, Mei, Yue, Xiao, Chen, Weicai, Zhang, Zhuo, Wang, Congrong, Zhou, Yong, Zhu, Linyong, Ju, Zhenyu, Loscalzo, Joseph, Yang, Yi, Zhao, Yuzheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323873/
https://ncbi.nlm.nih.gov/pubmed/32197067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.02.017
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