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The Spread of Ras Activity Triggered by Activation of a Single Dendritic Spine

In neurons, individual dendritic spines isolate NMDA receptor-mediated Ca(2+) accumulations from the dendrite and other spines. However, it is not known to what extent spines compartmentalize signaling events downstream of Ca(2+) influx. We combined two-photon fluorescence lifetime imaging (FLIM) wi...

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Detalhes bibliográficos
Main Authors: Harvey, Christopher D., Yasuda, Ryohei, Zhong, Haining, Svoboda, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745709/
https://ncbi.nlm.nih.gov/pubmed/18556515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1159675
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