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Long-Distance Integration of Nuclear ERK Signaling Triggered by Activation of a Few Dendritic Spines
The late phase of long-term potentiation (LTP) at glutamatergic synapses, which is thought to underlie long-lasting memory, requires gene transcription in the nucleus. However, the mechanism by which signaling initiated at synapses is transmitted into the nucleus to induce transcription has remained...
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| Pubblicato in: | Science |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318497/ https://ncbi.nlm.nih.gov/pubmed/24288335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245622 |
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