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Long-Distance Integration of Nuclear ERK Signaling Triggered by Activation of a Few Dendritic Spines

The late phase of long-term potentiation (LTP) at glutamatergic synapses, which is thought to underlie long-lasting memory, requires gene transcription in the nucleus. However, the mechanism by which signaling initiated at synapses is transmitted into the nucleus to induce transcription has remained...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Zhai, Shenyu, Ark, Eugene D., Parra-Bueno, Paula, Yasuda, Ryohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318497/
https://ncbi.nlm.nih.gov/pubmed/24288335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245622
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