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Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors

Heme is an essential cofactor and signaling molecule. Heme acquisition by proteins and heme signaling are ultimately reliant on the ability to mobilize labile heme (LH). However, the properties of LH pools, including concentration, oxidation state, distribution, speciation, and dynamics, are poorly...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hanna, David A., Harvey, Raven M., Martinez-Guzman, Osiris, Yuan, Xiaojing, Chandrasekharan, Bindu, Raju, Gheevarghese, Outten, F. Wayne, Hamza, Iqbal, Reddi, Amit R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941510/
https://ncbi.nlm.nih.gov/pubmed/27247412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523802113
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