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One ring to bring them all and in the darkness bind them: The Trafficking of Heme without Deliverers.

Heme, as a hydrophobic iron-containing organic ring, is lipid soluble and can interact with biological membranes. The very same properties of heme that nature exploits to support life also renders heme potentially cytotoxic. In order to utilize heme, while also mitigating its toxicity, cells are cha...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Chambers, Ian G., Willoughby, Mathilda M., Hamza, Iqbal, Reddi, Amit R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756907/
https://ncbi.nlm.nih.gov/pubmed/33022276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2020.118881
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