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Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes

Tricyclic antidepressants such as amitriptyline (AMT) have been reported to have adverse side effects on cardiac performance. AMT effects on Ca handling in ventricular myocytes, however, are not well understood. Therefore, we investigated AMT action on sarcoplasmic reticulum (SR) Ca release in ventr...

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Bibliografiske detaljer
Main Authors: Zima, Aleksey V., Qin, Jia, Fill, Michael, Blatter, Lothar A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614574/
https://ncbi.nlm.nih.gov/pubmed/18790837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00523.2008
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