Allelic variance between GRM6 mutants, Grm6(nob3) and Grm6(nob4) results in differences in retinal ganglion cell visual responses

An electroretinogram (ERG) screen identified a mouse with a normal a-wave but lacking a b-wave, and as such it was designated no b-wave3 (nob3). The nob3 phenotype mapped to chromosome 11 in a region containing the metabotropic glutamate receptor 6 gene (Grm6). Sequence analyses of cDNA identified a...

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Autori principali: Maddox, Dennis M, Vessey, Kirstan A, Yarbrough, Gary L, Invergo, Brandon M, Cantrell, Donald R, Inayat, Samsoon, Balannik, Victoria, Hicks, Wanda L, Hawes, Norman L, Byers, Shannon, Smith, Richard S, Hurd, Ron, Howell, Douglas, Gregg, Ronald G., Chang, Bo, Naggert, Jürgen K, Troy, John B, Pinto, Lawrence H, Nishina, Patsy M, McCall, Maureen A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614010/
https://ncbi.nlm.nih.gov/pubmed/18687716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.157289
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